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About

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Dr. Lobel’s Full BiographyDr. Darlene A. Lobel is a formerly board certified neurosurgeon who is internationally known as an expert in the treatment of essential tremor and other movement disorders.  She earned a Bachelor of Science degree from Duke University and her Medical Doctorate from Medical College of Georgia. She completed clinical fellowships in Stereotactic and Functional Neurosurgery and Epilepsy at UCLA and Emory, finishing training in 2007. She also completed two research fellowships, first in Grenoble, France, where she worked for two years with Professor Alim-Louis Benabid at Clinatec on the clinical protocol and implementation of a brain computer interface system, designed to aid quadriplegic patients. She then completed a fellowship in the Neural Engineering Laboratory at Mayo Clinic in Rochester, Minnesota, where she worked on the design and preclinical assessment of an intraspinal microstimulation system to restore neurologic function after spinal cord injury. Dr. Lobel worked for two years as a Neurosurgeon and Assistant Professor at University of Florida-Jacksonville and for nearly five years as a Neurosurgeon and Associate Professor of Neurosurgery and Biomedical Engineering at the Cleveland Clinic, where she had a busy practice treating patients with essential tremor and Parkinson’s disease. She also co-led an essential tremor support group for two years in the Cleveland area. Dr. Lobel is a renowned author with over 25 publications, including peer-reviewed manuscripts, books, and book chapters, and is an internationally acclaimed speaker. She has spent years researching ways to improve tremors, having served as a consultant and lead investigator on clinical trials in the U.S. and abroad. She also serves as an ad-hoc reviewer for neurosurgical and biomedical engineering journals, and serves on grant review panels, as reviewer and as chair. Her expertise is widely sought after as a reviewer, invited speaker, and as an expert in deep brain stimulation by other scientists and researchers.She has a passion for teaching, which extends not only to medical students and residents in training, but to her patients and to anyone who is looking to learn more about medical conditions.Dr. Lobel is an internationally acclaimed speaker and held leadership positions in the Council of State Neurosurgical Societies. She has served as Co-Investigator and Consultant in clinical trials in the US and in France, has authored numerous publications, including peer-reviewed manuscripts and book chapters, serves as an ad-hoc reviewer for neurosurgical and biomedical engineering journals, and serves on grant review panels, as reviewer and as chair. Her expertise is widely sought after as a reviewer, invited speaker, and as an expert in deep brain stimulation by other scientists and researchers.

Publications

  • Frizon LA, Hogue O, Achey R, Nagel S, Machado AM, Lobel DA. Quality of Life Improvement Following DBS for Parkinson’s Disease: Development of a prognostic model. Neurosurgery. 2018, in press.
  • Frizon LA, Shao J, Maldonado-Naranjo AL, Lobel DA, Fernandez H, et al. The Safety and efficacy of using the O-arm intraoperative imaging system for deep brain stimulation lead implantation. Neuromodulation. 2017 Dec 20.
  • Lee BL, Jones J, Lang M, Achey R, Dai L, Lobel DA, et al. Early outcomes after intrathecal baclofen therapy in ambulatory patients with multiple sclerosis. Journal of Neurosurgery. 2017:1-7.
  • Matias CM, Frizon LA, Nagel SN, Lobel DA, and Machado AM. Deep brain stimulation outcomes in patients implanted under general anesthesia with frame-based stereotaxis and intraoperative MRI. Journal of Neurosurgery. 2018:1-7.
  • Achey RL, Yamamoto E, Sexton D, Hammer C, Lee BS, Butler RS, Nagel SJ, Machado AG, and Lobel DA. Prediction of depression and anxiety via patient-assessed tremor severity, not physician-reported motor symptom severity, in patients with Parkinson’s disease or essential tremor who have undergone deep brain stimulation. Journal of Neurosurgery. 2018:1-10.
  • Maldonado-Naranjo AL, Frizon LA, Sabharwal NC, Xiao R, Hogue O, Lobel DA, et al. Rate of complications following spinal cord stimulation paddle electrode removal. Neuromodulation. 2017 Aug 22.
  • Frizon LA, Hogue O, Wathen C, Yamamoto E, Sabharwal NC, Jones J, Volovetz J, Maldonado-Naranjo AL, Lobel DA, Machado AG, Nagel SJ. Subsequent Pulse Generator Replacement Surgery Does Not Increase the Infection Rate in Patients With Deep Brain Stimulator Systems: A Review of 1537 Unique Implants at a Single Center. Neuromodulation. 2017 Jul;20(5):444-449.
  • Silva D, Matias  C, Bourne S, Nagel S, Machado A, Lobel D. Effects of chronic alcohol consumption on long-term outcomes of thalamic deep brain stimulation for essential tremor. .J Clin Neurosci. 2016 Sep;31:142-6. Epub 2016 Jul 9.
  • Lobel DA, Achey R, Brennan R, Rastogi A, Ajiboye AB. Enhancement of Cortical Signals to Improve Brain Machine Interface Performance by Inducing Mirror Neuron Network Activation. Neurosurgery, 2015 Aug;62 Suppl 1:201-2.
  • Lobel DA, Kahn M, Rosen CL, Pilitsis JG. Medical student education in neurosurgery: optional or essential? Teaching and Learning in Medicine, 2015;27(2):201-4.
  • Nagel SJ, Machado AM, Gale JT, Lobel DA, Pandya M. Preserving cortico-striatal function: Deep brain stimulation in Huntington’s Disease, Frontiers in Systems Neuroscience, 2015 Mar 11;9:32.
  • Grahn PJ, Lee KH, Kasabeh A, Mallory GW, Hachmann JT, Dube JR, Kimble CJ, Lobel DA, Bieber A, Jeong JH, Bennet K, Lujan JL. Wireless control of intraspinal microstimulation in a rodent model of paralysis. Journal of Neurosurgery, 2014 Dec 5:1-11.
  • Grahn PJ, Mallory GW, Berry BM, Hachmann JT, Lobel DA, and Lujan JL. Restoration of motor function following spinal cord injury: toward a closed-loop neural prosthesis. Frontiers in Neuroscience. 2014 Sep 17;8:296.
  • Matias CM, Amit A, Lempka SF, Ozinga JG 4th, Nagel SJ, Lobel DA, Machado AG. Long-term Outcomes After Replacement of Percutaneous Leads With Paddle Leads in a Retrospective Cohort of Patients With Spinal Cord Stimulation Systems. Neurosurgery. 2014 Oct;75(4):430-6.
  • Lobel DA and Lee KH.  Brain Machine Interface and Limb Reanimation Technologies: Restoring function after spinal cord injury through development of a bypass system.  Mayo Clinic Proceedings, 2014; 89(5): 708-714.
  • Lobel DA, Schirmer CM, Elder JB, Roitberg B. In Reply: Simulating Ventriculostomy.  Neurosurgery. Dec 30 2013. PMID: 24378830.
  • Hachmann JT, Jeong JH, Grahn PJ, Mallory GW, Evertz LQ, Bieber AJ, Lobel DA, Bennet KE, Lee KH, and  Lujan JL. Large animal model for development of functional restoration paradigms using epidural and intraspinal stimulation. PLOS ONE. 2013; 8(12): e81443.
  • Ghobrial GM, Anderson PA, Chitale R, Campbell PG, Lobel DA, and Harrop JS. Simulated Spinal Cerebrospinal Fluid Leak Repair: an Educational Model with Didactic and Technical Components. Neurosurgery. 2013; 73(Suppl): S111-115.
  • Chitale R, Ghobrial GM, Lobel D, and Harrop J.  Simulated Lumbar Minimally Invasive Surgery Educational Model With Didactic and Technical Components. Neurosurgery. 2013; 73(Suppl): S107-110.
  • Schirmer CM, Elder JB, Roitberg B, and Lobel DA. Virtual Reality Based Simulation Training for Ventriculostomy: An Evidence Based Approach. Neurosurgery. 2013; 73(Suppl): S66-73.
  • Lobel DA, Elder JB, Schirmer CM, Bowyer M, and Rezai AR.  A Novel Craniotomy Simulator Provides a Validated Method to Enhance Education in the Management of Traumatic Brain Injury.  Neurosurgery.  2013; 73(Suppl): S57-65.
  • Harrop JS, Lobel DA, Bendock B, Sharan A, Rezai AR. Developing Neurosurgical Simulation: An Overview. Neurosurgery. 2013; 73(Suppl): S25-29.
  • Mazzola CA, Lobel DA, Krishnamurthy S, Bloomgarden GM, Benzil DL. Efficacy of Neurosurgery Resident Education in the New Millenium: The 2008 Council of State Neurosurgical Societies Post-Residency Survey Results. Neurosurgery. August 2010; 67(2):225-233.
  • Tang M and Lobel DA. Severe Traumatic Brain Injury: Maximizing outcomes. Mount Sinai Journal of Medicine. 2009;76(2):119-128.
  • Hadman M, Chiu F-C, Lobel D, and Borlongan CV.  Commentary: Standardized Embryonic Tissue Collection and Hibernation Procedures, and MRI-Based Graft Assessment: Advancing Neural Transplantation Therapy for Huntington’s Disease.  Cell Transplantation. 2003; 12(7): 677-678.
  • Lobel DA, Hadman M, Sanberg PR, and Borlongan CV.  Early Intracerebral and Intra-arterial Transplantation of Human Umbilical Cord Blood Cells into an Ischemic Rat Brain Model.  Experimental Neurology. 2003; 181(1):97-98.

    • Invited, Non-Peer Reviewed

  • Harrop JS and Lobel DA.  Simulation Symposium: Simulation-based Neurosurgical Training.  Congress Quarterly.  Fall 2012.
  • Lobel DA, Rezai AR, and Harrop JS. Simulation Symposium-PC11:Simulation-based Neurosurgical Training. Congress Quarterly. Fall 2011.
  • Lobel DA and Rezai AR. Frontiers in Neurosurgery: Simulation in Resident Education. Congress Quarterly. Summer 2011.
  • Lobel DA. Robotics and Technology in Education. Congress Quarterly. Spring 2011.
  • Lobel DA, Park YP, and Lee MR. Surgical Treatment of Epilepsy in Children. Contemporary Neurosurgery.  2004; 26(2):1-8.

    • Book Chapters

  • Lobel DA, Lee MR:  Brain Stem Gliomas in Goodrich JT (ed):  Neurosurgical Operative Atlas (2nd Edition):  Pediatric Neurosurgery, Thieme, 2008, pp 275-280.
  • Lobel DA, Lee MR, Duhaime A-C:  Pediatric Intensive Care Unit Management of Neurosurgical Disease in Wheeler DS, Wong HR, Shanley TP (eds):  Pediatric Critical Care Medicine:  Basic Science and Clinical Evidence, Springer, 2007, pp 884-893.

    • Books

  • Mayo MD FAANS, Darlene A. Stop Spilling Your Soup! The Complete Essential Tremor Solution. Stop Spilling Your Soup, LLC, Jacksonville, FL, 2018.

    • Presentations

  • Intracranial Hemorrhage in the Hemodialysis Population, Georgia Neurosurgical Society, Sea Island, Georgia, May 25, 2001
  • Management of Intracranial Hemorrhage in Hemodialysis Patients. Neurology Grand Rounds, Medical College of Georgia, Augusta, Georgia, July 19, 2001
  • Outcome of Hemodialysis Patients Presenting with Intracranial Hemorrhage Managed by Surgical vs. Medical Therapy, Southern Neurosurgical Society, Orlando, Florida, March 15, 2003
  • Brain Cell Replacement Therapy for Parkinson’s Disease and Stroke: From Bench to Bedside,Poster presentation, Augusta VAMC Research Week, Augusta, Georgia, April 24, 2003
  • Early Intracerebral and Intra-arterial Transplantation of a Human Umbilical Cord Blood Cell Line into an Ischemic Rat Brain Model, American Society for Neural Transplantation and Repair, Clearwater Beach, Florida, May 2, 2003
  • Neural Transplantation in Acute and Chronic Neurological Disorders, Neurosurgery Grand Rounds, Medical College of Georgia, Augusta, Georgia, June 6, 2003
  • Intracerebral Transplantation of Human Umbilical Cord Blood in Acute Stroke, Congress of Neurological Surgeons, Denver, Colorado, October 20, 2003
  • Recent Experience in Pediatric Epilepsy Surgery at the Medical College of Georgia Children’s Medical Center, Georgia Neurosurgical Society, Atlanta, Georgia, November 22, 2003
  • Children with Tethered Cord and Imperforate Anus May Benefit from Early Release of Tethered Cord, Georgia Neurosurgical Society, Sea Island, Georgia, May 30, 2004
  • Early Surgical Release of Tethered Cord May Benefit Children with a History of Imperforate Anus, Congress of Neurological Surgeons, San Francisco, California, October 20, 2004
  • Surgical Treatment of Pineal Region Tumors, Neurosurgery Grand Rounds, Medical College of Georgia, Augusta, Georgia, March 25, 2005
  • Minocycline Improves Functional Outcome in a Rodent Epidural Hematoma Model, Congress of Neurological Surgeons, Boston, Massachusetts, October 10, 2005
  • Closed Loop Responsive Neurostimulator (RNS) for Epilepsy, Georgia Neurosurgical Society Meeting, Sea Island, Georgia, May 28, 2006
  • Follow-up Results with a Closed Loop Stimulation System in the Control of Focal Epilepsy, American Society for Stereotactic and Functional Neurosurgery, Boston, Massachusetts, June 3, 2006
  • Novel Techniques in the Surgical Management of Epilepsy, Emory Epilepsy Symposium: Medical and Surgical Therapeutic Advances in Epilepsy, Atlanta, Georgia, February 3, 2007
  • Surgical Treatment of Parkinson’s Disease, Neurology Grand Rounds, University of Florida-Jacksonville, November 6, 2007
  • Surgical Management of Parkinson’s Disease, Activa Parkinson’s Control Therapy Seminar, University of Florida-Jacksonville, Jacksonville, Florida, January 17, 2008
  • Emerging Applications for Deep Brain Stimulation, Neurology Grand Rounds, University of Florida-Jacksonville, Jacksonville, Florida, June 25, 2008
  • Deep Brain Stimulation for Parkinson’s Disease, Parkinson’s Disease Support Group, Dalton, Georgia, September, 2009
  • Post-Residency Survey Reveals Critical Education Issues: Results of the Council of State Neurosurgical Society (CSNS) Survey, Congress of Neurological Surgeons, New Orleans, Louisiana, October 2009
  • Deep Brain Stimulation for Parkinson’s Disease: Surgery, Northeast Georgia Medical Center, Gainesville, Georgia, December 17, 2009
  • Deep Brain Stimulation for Parkinson’s Disease, Parkinson’s Disease Support Group, Cartersville, Georgia, March 4, 2010
  • Analysis of Utilization Management or PEER to PEER review, Plenary session presentation, Council of State Neurosurgical Societies Spring Meeting, Philadelphia, Pennsylvania, April 30, 2010
  • Virtual Reality and Simulation in Neurosurgery Resident Training, Plenary session presentation, Council of State Neurosurgical Societies Spring Meeting, Philadelphia, Pennsylvania, April 30, 2010
  • Simulation in Neurosurgery, CNS Simulation Committee Meeting, Philadelphia, Pennsylvania, August 15, 2010
  • Medical Student Education in Neurosurgery: Trivial or Vital? Plenary session presentation, Council of State Neurosurgical Societies Fall Meeting, Washington, DC, September 30, 2011
  • Brain Machine Interface: Innovations and Applications, Neurosurgery Grand Rounds, Mayo Clinic, January 18, 2013
  • Brain Machine Interface Directed Limb Reanimation, 3rd Annual Neurosurgery Research Forum, Mayo Clinic, Rochester, Minnesota, February 11, 2013
  • Brain Machine Interface: Past, Present, and Future, Mayo Clinic, Rochester, Minnesota, February 21, 2013
  • Standardization of Surgical Procedures Involving Animals” lecture series, Mayo Clinic, Rochester, Minnesota, March 8, 2013 and March 15, 2013
  • Deep Brain Stimulation: Our Most Memorable Cases, Parkinson’s Disease for the Busy Clinician Symposium, Cleveland Convention Center, Cleveland, Ohio, March 9, 2014
  • Brain Machine Interface: Bypass systems to restore neurologic function, Cleveland Clinic Department of Biomedical Engineering, Cleveland, Ohio, May 9, 2014
  • Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans: Journal Club presentation, Cleveland Clinic Department of Anesthesiology, Cleveland, Ohio, June 20, 2014
  • Brain Machine Interface Systems to Restore Neurological Function after Paralysis. Cleveland Clinic Department of Neurology, Grand Rounds, Cleveland, Ohio, September 8, 2014
  • Updates in Deep Brain Stimulation. Advances in Neurological Therapeutics Conference, Las Vegas, Nevada, October 11, 2014
  • Brain Machine Interface in Cervical Spinal Cord Injury. Ohio State Neurosurgical Society, Columbus, Ohio, April 25, 2015
  • Enhancement of Cortical Signals to Improve Brain Machine Interface Performance by Inducing Mirror Neuron Network Activation: Choice Abstracts. Congress of Neurological Surgeons, New Orleans, Louisiana, September 27, 2015
  • Spinal Cord Stimulation: Indications and Outcomes. Essentials for the Spine Care Clinician, Cleveland, Ohio, November 7, 2015
  • Deep Brain Stimulation Surgery: Practice Building and Coding. American Society for Stereotactic and Functional Neurosurgery, Chicago, Illinois, June 18, 2016
  • ICD-10: Case based coding in Stereotactic and Functional Neurosurgery, Congress of Neurological Surgeons, San Diego, California, September 24, 2016
  • Simulation in Stereotactic and Functional Neurosurgery. Stereotactic and Functional Hands On Workshop, Denver, Colorado, November 4, 2016
  • Role of Virtual Reality Based Imagery in Recovery of Motor Function after Spinal Cord Injury, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, September 22, 2017

    • Visiting Professorships

  • Stem Cell Therapy: Pearls and Pitfalls, Grand rounds, Neuroscience Center Research Group, Medical University of South Carolina, Charleston, South Carolina, December 8, 2004
  • BrainLAB Image Fusion Guides Closed Loop Stimulator Implant, Invited lecture, BrainLAB Residents Academy, Munich, Germany, April 4, 2006
  • Epilepsy Surgery in the Modern Era, Grand rounds, Kansas University Medical Center, Kansas City, Kansas, August 25, 2006
  • CSNS Post-Residency Survey Results, Invited lecture, Society of Neurological Surgeons, Salt Lake City, Utah, May 19, 2009
  • Parkinson’s Disease New Procedure: Deep Brain Stimulation, Continuing Medical Education Grand Rounds Lecturer, Northeast Georgia Medical Center, March 19, 2010
  • Deep Brain Stimulation for Parkinson Disease, Keynote speaker, Southeastern Parkinson Disease Conference, Atlanta, Georgia, October 16, 2010
  • Optimizing the Brain Computer Interface: The Clinatec Experience: Transforming theory to practical applications, Invited plenary session presentation, LETI Annual Review, Grenoble, France, June 19, 2012
  • Role of Deep Brain Stimulation in Movement Disorders, Hot Topics in Neurology and Neurosurgery for the Primary Care Clinician, Invited lecture, Mayo Clinic, Rochester, Minnesota, June 7, 2013

    • Media Experience

  • “Tremors or ‘Shaking Hands’”, New Day Cleveland, Fox 8 News, Cleveland, Ohio, May 19, 2016. http://mms.tveyes.com/MediaCenterPlayer.aspx?u=aHR0cDovL21lZGlhY2VudGVyLnR2ZXllcy5jb20vZG93bmxvYWRnYXRld2F5LmFzcHg%2FVXNlcklEPTI4NjA5MyZNRElEPTYxODQzNTMmTURTZWVkPTQ3NzMmVHlwZT1NZWRpYQ%3D%3D&expand=true
  • “Naturally Controlled Artificial Limbs”, Cleveland Clinic Top Ten Medical Innovations for 2016,  October 28, 2015, http://health.clevelandclinic.org/2015/10/amazing-science-top-10-medical-innovations-2016/
  • “Thoughts Move Paralyzed Muscles”, Inside Science TV, American Institute of Physics. June 24, 2015, https://www.insidescience.org/content/thoughts-move-paralyzed-muscles/2971
  • “ Deep Brain Stimulation more comfortable for patients”, Health Hub, Cleveland Clinic, November 17, 2014, http://health.clevelandclinic.org/2014/11/deep-brain-stimulation-now-more-comfortable-for-patients/
  • “Neurorestoration in Parkinson’s Disease”, Spotlight Channel 5, Cleveland, Ohio, September 4, 2014, http://www.newsnet5.com/marketplace/spotlight5/cleveland-clinic-darlene-lobel-md
  • “Surgery provides hope for minister with Parkinson’s”, Youngstown Vindicator, Youngstown, Ohio, August 19, 2014,  http://www.vindy.com/news/2014/aug/19/surgery-provides-hope-for-minister-with-/?print
  • “Deep Brain Stimulation for Movement Disorders”, Cleveland Clinic Health Chat, July 28, 2014
  • “Pacemaker for the Brain Offers Treatment Options”, 700 Club, Christian Broadcast Network, June 2014, http://www.cbn.com/tv/3643937052001
  • “Relief of Parkinson’s Disease: the Bill Gibbs Story”, Northeast Georgia Physicians Group Spotlight, November 2010, http://www.ngpg.org/videos/BillGibbs.html
  • “Deep Brain Stimulation for Parkinson Disease”, Webcast, 5th Annual Southeastern Parkinson Disease Conference, October 16, 2010, http://www.gaparkinsons.org/2010%20SPDC%20Landing.html
  • “Postcall Fatigue Does Not Appear to Affect Neurosurgery Residents’ Psychomotor Skills”, Medscape Medical News, May 13, 2010
  • “Comorbidities Increase Cost, Length of Stay for Spine Surgery Patients”, Medscape Medical News, May 11, 2010
  • “Changing lives: Procedure can help control symptoms of Parkinson’s”, The Gainesville Times, November 9, 2009
  • “Buddy Wells: Georgia boy back on pitcher’s mound after ATV accident”, University of Florida-Shands-Jacksonville Spotlight, June 2008,  http://jax.shands.org/spotlight/wells.asp
  • “Deep Brain Stimulation for Movement Disorders”, Shands Healthcast, University of Florida-Shands-Jacksonville, May 2008, http://jax.shands.org/healthcast/
  • “Tai Chi Treatment for Parkinson’s Disease”, First Coast News (Channel 12) Broadcast, Jacksonville, Florida, April 24, 2008

    • [/av_textblock]

    [/av_three_fifth][/av_section]

    Publications

    1. Frizon LA, Hogue O, Achey R, Nagel S, Machado AM, Lobel DA. Quality of Life Improvement Following DBS for Parkinson’s Disease: Development of a prognostic model. Neurosurgery. 2018, in press.
    2. Frizon LA, Shao J, Maldonado-Naranjo AL, Lobel DA, Fernandez H, et al. The Safety and efficacy of using the O-arm intraoperative imaging system for deep brain stimulation lead implantation. Neuromodulation. 2017 Dec 20.
    3. Lee BL, Jones J, Lang M, Achey R, Dai L, Lobel DA, et al. Early outcomes after intrathecal baclofen therapy in ambulatory patients with multiple sclerosis. Journal of Neurosurgery. 2017:1-7.
    4. Matias CM, Frizon LA, Nagel SN, Lobel DA, and Machado AM. Deep brain stimulation outcomes in patients implanted under general anesthesia with frame-based stereotaxis and intraoperative MRI. Journal of Neurosurgery. 2018:1-7.
    5. Achey RL, Yamamoto E, Sexton D, Hammer C, Lee BS, Butler RS, Nagel SJ, Machado AG, and Lobel DA. Prediction of depression and anxiety via patient-assessed tremor severity, not physician-reported motor symptom severity, in patients with Parkinson’s disease or essential tremor who have undergone deep brain stimulation. Journal of Neurosurgery. 2018:1-10.
    6. Maldonado-Naranjo AL, Frizon LA, Sabharwal NC, Xiao R, Hogue O, Lobel DA, et al. Rate of complications following spinal cord stimulation paddle electrode removal. Neuromodulation. 2017 Aug 22.
    7. Frizon LA, Hogue O, Wathen C, Yamamoto E, Sabharwal NC, Jones J, Volovetz J, Maldonado-Naranjo AL, Lobel DA, Machado AG, Nagel SJ. Subsequent Pulse Generator Replacement Surgery Does Not Increase the Infection Rate in Patients With Deep Brain Stimulator Systems: A Review of 1537 Unique Implants at a Single Center. Neuromodulation. 2017 Jul;20(5):444-449.
    8. Silva D, Matias  C, Bourne S, Nagel S, Machado A, Lobel D. Effects of chronic alcohol consumption on long-term outcomes of thalamic deep brain stimulation for essential tremor. .J Clin Neurosci. 2016 Sep;31:142-6. Epub 2016 Jul 9.
    9. Lobel DA, Achey R, Brennan R, Rastogi A, Ajiboye AB. Enhancement of Cortical Signals to Improve Brain Machine Interface Performance by Inducing Mirror Neuron Network Activation. Neurosurgery, 2015 Aug;62 Suppl 1:201-2.
    10. Lobel DA, Kahn M, Rosen CL, Pilitsis JG. Medical student education in neurosurgery: optional or essential? Teaching and Learning in Medicine, 2015;27(2):201-4.
    11. Nagel SJ, Machado AM, Gale JT, Lobel DA, Pandya M. Preserving cortico-striatal function: Deep brain stimulation in Huntington’s Disease, Frontiers in Systems Neuroscience, 2015 Mar 11;9:32.
    12. Grahn PJ, Lee KH, Kasabeh A, Mallory GW, Hachmann JT, Dube JR, Kimble CJ, Lobel DA, Bieber A, Jeong JH, Bennet K, Lujan JL. Wireless control of intraspinal microstimulation in a rodent model of paralysis. Journal of Neurosurgery, 2014 Dec 5:1-11.
    13. Grahn PJ, Mallory GW, Berry BM, Hachmann JT, Lobel DA, and Lujan JL. Restoration of motor function following spinal cord injury: toward a closed-loop neural prosthesis. Frontiers in Neuroscience. 2014 Sep 17;8:296.
    14. Matias CM, Amit A, Lempka SF, Ozinga JG 4th, Nagel SJ, Lobel DA, Machado AG. Long-term Outcomes After Replacement of Percutaneous Leads With Paddle Leads in a Retrospective Cohort of Patients With Spinal Cord Stimulation Systems. Neurosurgery. 2014 Oct;75(4):430-6.
    15. Lobel DA and Lee KH.  Brain Machine Interface and Limb Reanimation Technologies: Restoring function after spinal cord injury through development of a bypass system.  Mayo Clinic Proceedings, 2014; 89(5): 708-714.
    16. Lobel DA, Schirmer CM, Elder JB, Roitberg B. In Reply: Simulating Ventriculostomy.  Neurosurgery. Dec 30 2013. PMID: 24378830.
    17. Hachmann JT, Jeong JH, Grahn PJ, Mallory GW, Evertz LQ, Bieber AJ, Lobel DA, Bennet KE, Lee KH, and  Lujan JL. Large animal model for development of functional restoration paradigms using epidural and intraspinal stimulation. PLOS ONE. 2013; 8(12): e81443.
    18. Ghobrial GM, Anderson PA, Chitale R, Campbell PG, Lobel DA, and Harrop JS. Simulated Spinal Cerebrospinal Fluid Leak Repair: an Educational Model with Didactic and Technical Components. Neurosurgery. 2013; 73(Suppl): S111-115.
    19. Chitale R, Ghobrial GM, Lobel D, and Harrop J.  Simulated Lumbar Minimally Invasive Surgery Educational Model With Didactic and Technical Components. Neurosurgery. 2013; 73(Suppl): S107-110.
    20. Schirmer CM, Elder JB, Roitberg B, and Lobel DA. Virtual Reality Based Simulation Training for Ventriculostomy: An Evidence Based Approach. Neurosurgery. 2013; 73(Suppl): S66-73.
    21. Lobel DA, Elder JB, Schirmer CM, Bowyer M, and Rezai AR.  A Novel Craniotomy Simulator Provides a Validated Method to Enhance Education in the Management of Traumatic Brain Injury.  Neurosurgery.  2013; 73(Suppl): S57-65.
    22. Harrop JS, Lobel DA, Bendock B, Sharan A, Rezai AR. Developing Neurosurgical Simulation: An Overview. Neurosurgery. 2013; 73(Suppl): S25-29.
    23. Mazzola CA, Lobel DA, Krishnamurthy S, Bloomgarden GM, Benzil DL. Efficacy of Neurosurgery Resident Education in the New Millenium: The 2008 Council of State Neurosurgical Societies Post-Residency Survey Results. Neurosurgery. August 2010; 67(2):225-233.
    24. Tang M and Lobel DA. Severe Traumatic Brain Injury: Maximizing outcomes. Mount Sinai Journal of Medicine. 2009;76(2):119-128.
    25. Hadman M, Chiu F-C, Lobel D, and Borlongan CV.  Commentary: Standardized Embryonic Tissue Collection and Hibernation Procedures, and MRI-Based Graft Assessment: Advancing Neural Transplantation Therapy for Huntington’s Disease.  Cell Transplantation. 2003; 12(7): 677-678.
    26. Lobel DA, Hadman M, Sanberg PR, and Borlongan CV.  Early Intracerebral and Intra-arterial Transplantation of Human Umbilical Cord Blood Cells into an Ischemic Rat Brain Model.  Experimental Neurology. 2003; 181(1):97-98.

    Invited, Non-Peer Reviewed

    1. Harrop JS and Lobel DA.  Simulation Symposium: Simulation-based Neurosurgical Training.  Congress Quarterly.  Fall 2012.
    2. Lobel DA, Rezai AR, and Harrop JS. Simulation Symposium-PC11:Simulation-based Neurosurgical Training. Congress Quarterly. Fall 2011.
    3. Lobel DA and Rezai AR. Frontiers in Neurosurgery: Simulation in Resident Education. Congress Quarterly. Summer 2011.
    4. Lobel DA. Robotics and Technology in Education. Congress Quarterly. Spring 2011.
    5. Lobel DA, Park YP, and Lee MR. Surgical Treatment of Epilepsy in Children. Contemporary Neurosurgery.  2004; 26(2):1-8.

    Book Chapters

    1. Lobel DA, Lee MR:  Brain Stem Gliomas in Goodrich JT (ed):  Neurosurgical Operative Atlas (2nd Edition):  Pediatric Neurosurgery, Thieme, 2008, pp 275-280.
    2. Lobel DA, Lee MR, Duhaime A-C:  Pediatric Intensive Care Unit Management of Neurosurgical Disease in Wheeler DS, Wong HR, Shanley TP (eds):  Pediatric Critical Care Medicine:  Basic Science and Clinical Evidence, Springer, 2007, pp 884-893.

    Books

    1. Mayo MD FAANS, Darlene A. Stop Spilling Your Soup! The Complete Essential Tremor Solution. Stop Spilling Your Soup, LLC, Jacksonville, FL, 2018.

    Presentations

    1. Intracranial Hemorrhage in the Hemodialysis Population, Georgia Neurosurgical Society, Sea Island, Georgia, May 25, 2001
    2. Management of Intracranial Hemorrhage in Hemodialysis Patients. Neurology Grand Rounds, Medical College of Georgia, Augusta, Georgia, July 19, 2001
    3. Outcome of Hemodialysis Patients Presenting with Intracranial Hemorrhage Managed by Surgical vs. Medical Therapy, Southern Neurosurgical Society, Orlando, Florida, March 15, 2003
    4. Brain Cell Replacement Therapy for Parkinson’s Disease and Stroke: From Bench to Bedside,Poster presentation, Augusta VAMC Research Week, Augusta, Georgia, April 24, 2003
    5. Early Intracerebral and Intra-arterial Transplantation of a Human Umbilical Cord Blood Cell Line into an Ischemic Rat Brain Model, American Society for Neural Transplantation and Repair, Clearwater Beach, Florida, May 2, 2003
    6. Neural Transplantation in Acute and Chronic Neurological Disorders, Neurosurgery Grand Rounds, Medical College of Georgia, Augusta, Georgia, June 6, 2003
    7. Intracerebral Transplantation of Human Umbilical Cord Blood in Acute Stroke, Congress of Neurological Surgeons, Denver, Colorado, October 20, 2003
    8. Recent Experience in Pediatric Epilepsy Surgery at the Medical College of Georgia Children’s Medical Center, Georgia Neurosurgical Society, Atlanta, Georgia, November 22, 2003
    9. Children with Tethered Cord and Imperforate Anus May Benefit from Early Release of Tethered Cord, Georgia Neurosurgical Society, Sea Island, Georgia, May 30, 2004
    10. Early Surgical Release of Tethered Cord May Benefit Children with a History of Imperforate Anus, Congress of Neurological Surgeons, San Francisco, California, October 20, 2004
    11. Surgical Treatment of Pineal Region Tumors, Neurosurgery Grand Rounds, Medical College of Georgia, Augusta, Georgia, March 25, 2005
    12. Minocycline Improves Functional Outcome in a Rodent Epidural Hematoma Model, Congress of Neurological Surgeons, Boston, Massachusetts, October 10, 2005
    13. Closed Loop Responsive Neurostimulator (RNS) for Epilepsy, Georgia Neurosurgical Society Meeting, Sea Island, Georgia, May 28, 2006
    14. Follow-up Results with a Closed Loop Stimulation System in the Control of Focal Epilepsy, American Society for Stereotactic and Functional Neurosurgery, Boston, Massachusetts, June 3, 2006
    15. Novel Techniques in the Surgical Management of Epilepsy, Emory Epilepsy Symposium: Medical and Surgical Therapeutic Advances in Epilepsy, Atlanta, Georgia, February 3, 2007
    16. Surgical Treatment of Parkinson’s Disease, Neurology Grand Rounds, University of Florida-Jacksonville, November 6, 2007
    17. Surgical Management of Parkinson’s Disease, Activa Parkinson’s Control Therapy Seminar, University of Florida-Jacksonville, Jacksonville, Florida, January 17, 2008
    18. Emerging Applications for Deep Brain Stimulation, Neurology Grand Rounds, University of Florida-Jacksonville, Jacksonville, Florida, June 25, 2008
    19. Deep Brain Stimulation for Parkinson’s Disease, Parkinson’s Disease Support Group, Dalton, Georgia, September, 2009
    20. Post-Residency Survey Reveals Critical Education Issues: Results of the Council of State Neurosurgical Society (CSNS) Survey, Congress of Neurological Surgeons, New Orleans, Louisiana, October 2009
    21. Deep Brain Stimulation for Parkinson’s Disease: Surgery, Northeast Georgia Medical Center, Gainesville, Georgia, December 17, 2009
    22. Deep Brain Stimulation for Parkinson’s Disease, Parkinson’s Disease Support Group, Cartersville, Georgia, March 4, 2010
    23. Analysis of Utilization Management or PEER to PEER review, Plenary session presentation, Council of State Neurosurgical Societies Spring Meeting, Philadelphia, Pennsylvania, April 30, 2010
    24. Virtual Reality and Simulation in Neurosurgery Resident Training, Plenary session presentation, Council of State Neurosurgical Societies Spring Meeting, Philadelphia, Pennsylvania, April 30, 2010
    25. Simulation in Neurosurgery, CNS Simulation Committee Meeting, Philadelphia, Pennsylvania, August 15, 2010
    26. Medical Student Education in Neurosurgery: Trivial or Vital? Plenary session presentation, Council of State Neurosurgical Societies Fall Meeting, Washington, DC, September 30, 2011
    27. Brain Machine Interface: Innovations and Applications, Neurosurgery Grand Rounds, Mayo Clinic, January 18, 2013
    28. Brain Machine Interface Directed Limb Reanimation, 3rd Annual Neurosurgery Research Forum, Mayo Clinic, Rochester, Minnesota, February 11, 2013
    29. Brain Machine Interface: Past, Present, and Future, Mayo Clinic, Rochester, Minnesota, February 21, 2013
    30. Standardization of Surgical Procedures Involving Animals” lecture series, Mayo Clinic, Rochester, Minnesota, March 8, 2013 and March 15, 2013
    31. Deep Brain Stimulation: Our Most Memorable Cases, Parkinson’s Disease for the Busy Clinician Symposium, Cleveland Convention Center, Cleveland, Ohio, March 9, 2014
    32. Brain Machine Interface: Bypass systems to restore neurologic function, Cleveland Clinic Department of Biomedical Engineering, Cleveland, Ohio, May 9, 2014
    33. Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans: Journal Club presentation, Cleveland Clinic Department of Anesthesiology, Cleveland, Ohio, June 20, 2014
    34. Brain Machine Interface Systems to Restore Neurological Function after Paralysis. Cleveland Clinic Department of Neurology, Grand Rounds, Cleveland, Ohio, September 8, 2014
    35. Updates in Deep Brain Stimulation. Advances in Neurological Therapeutics Conference, Las Vegas, Nevada, October 11, 2014
    36. Brain Machine Interface in Cervical Spinal Cord Injury. Ohio State Neurosurgical Society, Columbus, Ohio, April 25, 2015
    37. Enhancement of Cortical Signals to Improve Brain Machine Interface Performance by Inducing Mirror Neuron Network Activation: Choice Abstracts. Congress of Neurological Surgeons, New Orleans, Louisiana, September 27, 2015
    38. Spinal Cord Stimulation: Indications and Outcomes. Essentials for the Spine Care Clinician, Cleveland, Ohio, November 7, 2015
    39. Deep Brain Stimulation Surgery: Practice Building and Coding. American Society for Stereotactic and Functional Neurosurgery, Chicago, Illinois, June 18, 2016
    40. ICD-10: Case based coding in Stereotactic and Functional Neurosurgery, Congress of Neurological Surgeons, San Diego, California, September 24, 2016
    41. Simulation in Stereotactic and Functional Neurosurgery. Stereotactic and Functional Hands On Workshop, Denver, Colorado, November 4, 2016
    42. Role of Virtual Reality Based Imagery in Recovery of Motor Function after Spinal Cord Injury, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, September 22, 2017

    Visiting Professorships

    1. Stem Cell Therapy: Pearls and Pitfalls, Grand rounds, Neuroscience Center Research Group, Medical University of South Carolina, Charleston, South Carolina, December 8, 2004
    2. BrainLAB Image Fusion Guides Closed Loop Stimulator Implant, Invited lecture, BrainLAB Residents Academy, Munich, Germany, April 4, 2006
    3. Epilepsy Surgery in the Modern Era, Grand rounds, Kansas University Medical Center, Kansas City, Kansas, August 25, 2006
    4. CSNS Post-Residency Survey Results, Invited lecture, Society of Neurological Surgeons, Salt Lake City, Utah, May 19, 2009
    5. Parkinson’s Disease New Procedure: Deep Brain Stimulation, Continuing Medical Education Grand Rounds Lecturer, Northeast Georgia Medical Center, March 19, 2010
    6. Deep Brain Stimulation for Parkinson Disease, Keynote speaker, Southeastern Parkinson Disease Conference, Atlanta, Georgia, October 16, 2010
    7. Optimizing the Brain Computer Interface: The Clinatec Experience: Transforming theory to practical applications, Invited plenary session presentation, LETI Annual Review, Grenoble, France, June 19, 2012
    8. Role of Deep Brain Stimulation in Movement Disorders, Hot Topics in Neurology and Neurosurgery for the Primary Care Clinician, Invited lecture, Mayo Clinic, Rochester, Minnesota, June 7, 2013

    Media Experience

    1. “Tremors or ‘Shaking Hands’”, New Day Cleveland, Fox 8 News, Cleveland, Ohio, May 19, 2016. http://mms.tveyes.com/MediaCenterPlayer.aspx?u=aHR0cDovL21lZGlhY2VudGVyLnR2ZXllcy5jb20vZG93bmxvYWRnYXRld2F5LmFzcHg%2FVXNlcklEPTI4NjA5MyZNRElEPTYxODQzNTMmTURTZWVkPTQ3NzMmVHlwZT1NZWRpYQ%3D%3D&expand=true
    2. “Naturally Controlled Artificial Limbs”, Cleveland Clinic Top Ten Medical Innovations for 2016,  October 28, 2015, http://health.clevelandclinic.org/2015/10/amazing-science-top-10-medical-innovations-2016/
    3. “Thoughts Move Paralyzed Muscles”, Inside Science TV, American Institute of Physics. June 24, 2015, https://www.insidescience.org/content/thoughts-move-paralyzed-muscles/2971
    4. “ Deep Brain Stimulation more comfortable for patients”, Health Hub, Cleveland Clinic, November 17, 2014, http://health.clevelandclinic.org/2014/11/deep-brain-stimulation-now-more-comfortable-for-patients/
    5. “Neurorestoration in Parkinson’s Disease”, Spotlight Channel 5, Cleveland, Ohio, September 4, 2014, http://www.newsnet5.com/marketplace/spotlight5/cleveland-clinic-darlene-lobel-md
    6. “Surgery provides hope for minister with Parkinson’s”, Youngstown Vindicator, Youngstown, Ohio, August 19, 2014,  http://www.vindy.com/news/2014/aug/19/surgery-provides-hope-for-minister-with-/?print
    7. “Deep Brain Stimulation for Movement Disorders”, Cleveland Clinic Health Chat, July 28, 2014
    8. “Pacemaker for the Brain Offers Treatment Options”, 700 Club, Christian Broadcast Network, June 2014, http://www.cbn.com/tv/3643937052001
    9. “Relief of Parkinson’s Disease: the Bill Gibbs Story”, Northeast Georgia Physicians Group Spotlight, November 2010, http://www.ngpg.org/videos/BillGibbs.html
    10. “Deep Brain Stimulation for Parkinson Disease”, Webcast, 5th Annual Southeastern Parkinson Disease Conference, October 16, 2010, http://www.gaparkinsons.org/2010%20SPDC%20Landing.html
    11. “Postcall Fatigue Does Not Appear to Affect Neurosurgery Residents’ Psychomotor Skills”, Medscape Medical News, May 13, 2010
    12. “Comorbidities Increase Cost, Length of Stay for Spine Surgery Patients”, Medscape Medical News, May 11, 2010
    13. “Changing lives: Procedure can help control symptoms of Parkinson’s”, The Gainesville Times, November 9, 2009
    14. “Buddy Wells: Georgia boy back on pitcher’s mound after ATV accident”, University of Florida-Shands-Jacksonville Spotlight, June 2008,  http://jax.shands.org/spotlight/wells.asp
    15. “Deep Brain Stimulation for Movement Disorders”, Shands Healthcast, University of Florida-Shands-Jacksonville, May 2008, http://jax.shands.org/healthcast/
    16. “Tai Chi Treatment for Parkinson’s Disease”, First Coast News (Channel 12) Broadcast, Jacksonville, Florida, April 24, 2008

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